Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 2/20 | 0.47 |
| ▸ | NOS1 | P29475 | 3/20 | 0.47 |
| ▸ | AXL | P30530 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29563426 | 1.00 | IDO1 (0.54) | IDO1HSP90AA1CDK2ALDH1A1HSD17B10 | |
| SCHEMBL27074503 | 0.96 | HPRT1 (0.54) | IDO1HSP90AA1CDK2ALDH1A1HSD17B10 | |
| SCHEMBL29450787 | 0.96 | HPRT1 (0.54) | IDO1HSP90AA1CDK2ALDH1A1HSD17B10 | |
| SCHEMBL30486 | 0.82 | IDO1 (0.48) | IDO1HSP90AA1CDK2ALDH1A1HSD17B10 | |
| SCHEMBL12321248 | 0.82 | NOS1 (0.56) | IDO1HSP90AA1CDK2ALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL999376 | 0.81 | IDO1 (0.47) | IDO1HSP90AA1CDK2ALDH1A1HSD17B10 | |
| SCHEMBL21514162 | 0.79 | METAP2 (0.66) | IDO1HSP90AA1CDK2ALDH1A1HSD17B10 | |
| SCHEMBL11229647 | 0.77 | ALDH1A1 (0.57) | IDO1HSP90AA1CDK2ALDH1A1HSD17B10 | |
| SCHEMBL29416140 | 0.76 | CDK4 (0.47) | IDO1ALDH1A1TDP1METAP2NOS1 | |
| SCHEMBL29424672 | 0.76 | CLK1 (0.43) | IDO1METAP2NOS1AXLFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530228-A | Condensed ring substituted dibenzofuran type organic compound, application thereof and organic electroluminescent device | 北京鼎材科技有限公司 | 2024-08-23 | — | — | CN | claimed |
| CN-118530227-A | Condensed ring substituted dibenzofuran type organic compound, application thereof and organic electroluminescent device | 北京鼎材科技有限公司 | 2024-08-23 | — | — | CN | claimed |
| CN-116606685-A | Water-soluble temper rolling liquid composition for non-degreased annealed steel sheet | 大同化学株式会社 | 2023-08-18 | — | — | CN | claimed |
| CN-113185535-A | Benzothiophene compound based on naphthalimide and preparation and application thereof | 北京化工大学 | 2021-07-30 | — | — | CN | claimed |
| CN-113121563-A | Thienophthalimide compound, thiophenethiol and preparation and application thereof | 北京化工大学 | 2021-07-16 | — | — | CN | claimed |
| US-10907093-B2 | Condensed cyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-02-02 | — | — | US | claimed |
| CN-110698476-A | Based on C3Symmetrical n-type organic semiconductor material and synthesis and application thereof | 北京化工大学 | 2020-01-17 | — | — | CN | claimed |
| US-20180105741-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-04-19 | — | — | US | claimed |
| EP-2336315-B1 | Enzymatic encoding methods for efficient synthesis of large libraries | NUEVOLUTION AS (DK) | 2017-07-19 | — | — | EP | claimed |
| WO-2017031050-A1 | MOLECULARLY TUNABLE HETEROGENEOUS CATALYSTS BY EDGE FUNCTIONALIZATION OF GRAPHITIC CARBONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-02-23 | — | — | WO | claimed |
| US-6849631-B2 | Semicarbazides and their uses | BRISTOL MYERS SQUIBB PHARMA COMPANY (US) | 2005-02-01 | — | — | US | claimed |
| EP-1453789-A2 | N,N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | Elan Pharmaceuticals, Inc. (US) | 2004-09-08 | — | — | EP | claimed |
| US-20040171881-A1 | N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives | PHARMACIA & UPJOHN COMPANY | 2004-09-02 | — | — | US | claimed |
| EP-1080075-B1 | PIPERIDIDINYL AND N-AMIDINOPIPERIDINYL DERIVATIVES | AVENTIS PHARMA INC (US) | 2004-08-11 | — | — | EP | claimed |
| EP-1351956-A1 | SEMICARBAZIDES AND THEIR USES AS CYCLIN DEPENDENT KINASE INHIBITORS | Bristol-Myers Squibb Pharma Company (US) | 2003-10-15 | — | — | EP | claimed |
| WO-2003040096-A2 | N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | ELAN PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | WO | claimed |
| US-20020091127-A1 | Semicarbazides and their uses | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-07-11 | — | — | US | claimed |
| WO-2002046182-A1 | SEMICARBAZIDES AND THEIR USES AS CYCLIN DEPENDENT KINASE INHIBITORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-06-13 | — | — | WO | claimed |
| EP-0143782-A1 | COAL-WATER DISPERSION. | FLUIDCARBON INTERNATIONAL AB (SE) | 1985-06-12 | — | — | EP | claimed |
| WO-1984001957-A1 | COAL-WATER DISPERSION | FLUIDCARBON INTERNATIONAL AB (SE) | 1984-05-24 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180105741-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | C1S, SCO2, CCND2 | IDO1 847/4885HSP90AA1 3003/4885CDK2 34/4885 |
| US-20040171881-A1 | N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives | BACE1, BACE2, PSEN1 | IDO1 2532/4885HSP90AA1 1979/4885CDK2 1650/4885 |
| US-10907093-B2 | Condensed cyclic compound and organic light-emitting device including the same | C1S, SCO2, CCND2 | IDO1 847/4885HSP90AA1 3003/4885CDK2 34/4885 |
| US-20020091127-A1 | Semicarbazides and their uses | CDK1, CCNA1, CDK17 | IDO1 347/4885HSP90AA1 3614/4885CDK2 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.