SCHEMBL30486

SCHEMBL30486

c1ccc2cc3c(ccc4[nH]ncc43)cc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.48
HSP90AA1 P07900 1/20 0.48
CDK2 P24941 1/20 0.48
ALDH1A1 P00352 1/20 0.43
HIF1A Q16665 1/20 0.43
CYP1B1 Q16678 1/20 0.43
HSD17B10 Q99714 1/20 0.43
METAP2 P50579 5/20 0.43
FGFR1 P11362 1/20 0.43
DYRK3 O43781 1/20 0.43
CLK1 P49759 1/20 0.43
CLK2 P49760 1/20 0.43
CLK3 P49761 1/20 0.43
GSK3B P49841 1/20 0.43
CDK5 Q00535 1/20 0.43
DYRK1A Q13627 1/20 0.43
CDK5R1 Q15078 1/20 0.43
DYRK2 Q92630 1/20 0.43
CLK4 Q9HAZ1 1/20 0.43
DYRK1B Q9Y463 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL999376 0.98 IDO1 (0.47) IDO1HSP90AA1CDK2ALDH1A1HIF1A
Pyrrole SCHEMBL27612136 0.92 IDO1 (0.42) IDO1HSP90AA1CDK2ALDH1A1HIF1A
SCHEMBL4141797 0.84 RAF1 (0.40) IDO1HSP90AA1CDK2MKNK1
SCHEMBL17255318 0.83 HASPIN (0.45) FGFR1CLK1DYRK1A
SCHEMBL29563426 0.82 IDO1 (0.54) IDO1HSP90AA1CDK2ALDH1A1HIF1A
SCHEMBL276443 0.82 IDO1 (0.54) IDO1HSP90AA1CDK2ALDH1A1HIF1A
SCHEMBL27074503 0.79 HPRT1 (0.54) IDO1HSP90AA1CDK2ALDH1A1HSD17B10
SCHEMBL29450787 0.79 HPRT1 (0.54) IDO1HSP90AA1CDK2ALDH1A1HSD17B10
SCHEMBL7208201 0.79 PTPRC (0.41) IDO1ALDH1A1KDM4EMEN1MAPT
SCHEMBL12321248 0.77 NOS1 (0.56) IDO1HSP90AA1CDK2ALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2919 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117715942-A Enhanced targeting using antibody-oligonucleotide conjugates 代码生物疗法公司 2024-03-15 CN claimed
EP-4301859-A1 ENHANCED TARGETING USING ANTIBODY-OLIGONUCLEOTIDE CONJUGATES Code Biotherapeutics, Inc. (US) 2024-01-10 EP claimed
WO-2022187586-A1 ENHANCED TARGETING USING ANTIBODY-OLIGONUCLEOTIDE CONJUGATES CODE BIOTHERAPEUTICS, INC. (US) 2022-09-09 WO claimed
US-20220202961-A1 IMAGING AND TREATMENT OF PATHOPHYSIOLOGIC CONDITIONS BY CERENKOV RADIATION WASHINGTON UNIVERSITY 2022-06-30 US claimed
WO-2021224419-A1 PHOTOOXIDATIVE INACTIVATION OF PATHOGENS INCLUDING SARS-CoV-2 Luminnova Health Limited (BS) 2021-11-11 WO claimed
US-20210154200-A1 7-BENZYL-4-(METHYLBENZYL)-2,4,6,7,8,9-HEXAHYDROIMIDAZO[1,2-A]PYRIDO[3,4-E]PYRIMIDIN-5 (1H)-ONE, SALTS THEREOF AND METHODS OF USING THE SAME IN COMBINATION THERAPY ONCOCEUTICS, INC. (US) 2021-05-27 US claimed
EP-3500271-A1 GENOME EDITING ENHANCERS Bluebird Bio, Inc. (US) 2019-06-26 EP claimed
US-20190169597-A1 GENOME EDITING ENHANCERS BLUEBIRD BIO, INC. (US) 2019-06-06 US claimed
CN-109715171-A Genome editor's enhancer 蓝鸟生物公司 2019-05-03 CN claimed
US-20190022044-A1 SALTS OF 5-AMINOLEVULINIC ACID AND DERIVATIVES ZHAO MING (US) 2019-01-24 US claimed
WO-1998026751-A1 ANHYDROUS COSMETIC COMPOSITION CONTAINING A FATTY CONSTITUENT AND A POLYMERIC COLOURING AGENT L'OREAL (FR) 1998-06-25 WO claimed
WO-1998026753-A1 COSMETIC COMPOSITION IN THE FORM OF AN AQUEOUS DISPERSION CONTAINING AT LEAST A POLYMERIC COLOURING AGENT L'OREAL (FR) 1998-06-25 WO claimed
WO-1998026757-A1 COSMETIC COMPOSITION IN THE FORM OF AN AQUEOUS GEL CONTAINING A POLYMERIC COLOURING AGENT L'OREAL (FR) 1998-06-25 WO claimed
WO-1998026754-A1 COSMETIC COMPOSITION IN THE FORM OF AN ORGANIC SOLUTION OR DISPERSION CONTAINING AT LEAST A POLYMERIC COLOURING AGENT L'OREAL (FR) 1998-06-25 WO claimed
WO-1998023690-A1 METHOD FOR PREPARING LIGHT-ABSORBING POLYMERIC COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 1998-06-04 WO claimed
EP-0445926-B1 Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation MILLIKEN RES CORP (US) 1996-08-21 EP claimed
EP-0605566-A1 LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN CHEMICAL COMPANY (US) 1994-07-13 EP claimed
WO-1993006147-A1 LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN KODAK COMPANY (US) 1993-04-01 WO claimed
US-5194463-A LIGHT-ABSORBING POLYURETHANE COMPOSITIONS AND THERMOPLASTIC POLYMERS COLORED THEREWITH EASTMAN KODAK COMPANY (US) 1993-03-16 US claimed
EP-0445926-A2 Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation MILLIKEN RESEARCH CORPORATION (US) 1991-09-11 EP claimed