Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.42 |
| ▸ | ACP3 | P15309 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27665187 | 0.88 | MEN1 (0.47) | MEN1ALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL27665568 | 0.85 | PNMT (0.46) | MEN1ALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL27644752 | 0.85 | GRM8 (0.41) | CES2SLC6A9 | |
| SCHEMBL23009730 | 0.83 | RIPK1 (0.40) | MEN1ALDH1A1CYP1A2POLBKMT2A | |
| SCHEMBL27665671 | 0.82 | ALDH1A1 (0.39) | MEN1ALDH1A1KMT2AACP3IDO1 | |
| SCHEMBL27644381 | 0.79 | HTR2A (0.49) | MEN1CYP1A2CYP3A4CYP2C9KMT2A | |
| SCHEMBL4992355 | 0.78 | PNMT (0.50) | MEN1ALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL27644704 | 0.78 | GRM2 (0.48) | MEN1CYP1A2KMT2AEPHX1GRM2 | |
| SCHEMBL27643982 | 0.77 | PNMT (0.48) | MEN1ALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL20090975 | 0.77 | PNMT (0.49) | MEN1ALDH1A1CYP1A2POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |