Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122883 | 0.85 | ACACB (0.45) | ACACBMAPTMTNR1AMTNR1BHDAC1 | |
| SCHEMBL1806289 | 0.79 | ACACB (0.43) | ACACBMAPTMTNR1AMTNR1BHDAC1 | |
| SCHEMBL12521736 | 0.79 | ALDH1A3 (0.48) | ACACBMAPTALDH1A3POLBGAA | |
| SCHEMBL27666109 | 0.79 | ALDH1A3 (0.54) | ALDH1A3POLBGAAKMT2A | |
| SCHEMBL27666317 | 0.78 | GAA (0.44) | ACACBMAPTMTNR1AMTNR1BGAA | |
| SCHEMBL9888683 | 0.77 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL8263616 | 0.77 | ACHE (0.42) | ACACBMAPTMTNR1AMTNR1BKMT2A | |
| SCHEMBL18754954 | 0.77 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL13064360 | 0.77 | ACHE (0.42) | ACACBMAPTMTNR1AMTNR1BKMT2A | |
| SCHEMBL25513374 | 0.77 | ACHE (0.42) | ACACBMAPTMTNR1AMTNR1BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |