SCHEMBL2764596

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4932031	0.90	PDE2A (0.39)	NR1H2NR1H3PDE2APTPN5TP53
	SCHEMBL2763790	0.87	PDE2A (0.37)	PDE2APTPN5TP53MAPTUTS2R
	Ethylamine SCHEMBL27563059	0.76	PDE2A (0.50)	PDE2APTPN5CYP2D6CYP2C9HIF1A
	SCHEMBL84043	0.74	PDE2A (0.53)	PDE2APTPN5CYP2D6CYP2C9HIF1A
	SCHEMBL14404367	0.72	KIF11 (0.47)	PDE2A
	Ammonia Solution, Strong SCHEMBL27642816	0.72	PDE2A (0.52)	PDE2APTPN5CYP2D6CYP2C9HIF1A
	SCHEMBL2763430	0.70	PDE2A (0.47)	PDE2APTPN5CYP2D6CYP2C9HIF1A
	SCHEMBL27654394	0.69	CES2 (0.45)	PDE2APTPN5UTS2RCYP2D6CYP2C9
	SCHEMBL5540984	0.69	PDE2A (0.46)	PDE2APTPN5CYP2D6CYP2C9HIF1A
	SCHEMBL29331540	0.69	PDE2A (0.46)	PDE2AACP3AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.