SCHEMBL4932031

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2764596	0.90	NR1H2 (0.43)	PDE2ATP53MAPTPTPN5NR1H2
	SCHEMBL2763790	0.89	PDE2A (0.37)	PDE2ACRHR1TP53MAPTKIF11
	Ethylamine SCHEMBL27563059	0.77	PDE2A (0.50)	PDE2AKIF11PTPN5MC4R
	SCHEMBL84043	0.75	PDE2A (0.53)	PDE2AKIF11PTPN5
	SCHEMBL2763430	0.74	PDE2A (0.47)	PDE2APTPN5
	SCHEMBL14404367	0.73	KIF11 (0.47)	PDE2AKIF11
	Ammonia Solution, Strong SCHEMBL27642816	0.73	PDE2A (0.52)	PDE2AKIF11PTPN5
	SCHEMBL5540984	0.70	PDE2A (0.46)	PDE2AKIF11PTPN5
	SCHEMBL14087362	0.69	PTPN5 (0.59)	PDE2AKIF11PTPN5
	SCHEMBL23058137	0.69	CRHR1 (0.40)	PDE2ACRHR1TP53MC4RUTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.