Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13338362 | 0.78 | KIF11 (0.46) | KIF11PDE2ACA1CA2HDAC8 | |
| SCHEMBL18427610 | 0.77 | KIF11 (0.49) | KIF11PDE2ACA1CA2HDAC8 | |
| SCHEMBL18685866 | 0.76 | KIF11 (0.52) | KIF11CA1CA2TAAR1ALDH1A1 | |
| SCHEMBL3099378 | 0.76 | MAOA (0.41) | CA1CA2TAAR1IDO1 | |
| Hydrochloric Acid SCHEMBL9879585 | 0.74 | MAOA (0.39) | NOS1TAAR1IDO1 | |
| SCHEMBL4932031 | 0.73 | PDE2A (0.39) | KIF11PDE2A | |
| SCHEMBL22651949 | 0.73 | KIF11 (0.42) | KIF11PDE2ACA1CA2HDAC8 | |
| SCHEMBL27752141 | 0.73 | KIF11 (0.44) | KIF11CA1CA2CA9TAAR1 | |
| SCHEMBL2764596 | 0.72 | NR1H2 (0.43) | PDE2A | |
| SCHEMBL13338543 | 0.72 | ALDH1A1 (0.48) | KIF11PDE2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007116314-A1 | N-PHENYL-1,1,1-TRIFLUOROMETHANESULFONAMIDE HYDRAZONE DERIVATIVE COMPOUNDS AND THEIR USAGE IN CONTROLLING PARASITES | SCHERING-PLOUGH LTD. (US) | 2007-10-18 | — | — | WO | disclosed |