Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 3/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313808 | 0.69 | MASP2 (0.44) | HPGDSNPY5R | |
| SCHEMBL9026285 | 0.69 | CYP2A6 (0.43) | HPGDSNPY5R | |
| SCHEMBL29207565 | 0.69 | CCR1 (0.31) | BTKCCR1CCR5CCR8 | |
| SCHEMBL30179265 | 0.69 | CCR1 (0.31) | BTKCCR1CCR5CCR8 | |
| SCHEMBL8816338 | 0.68 | PIN1 (0.43) | HPGDSNPY5RPIN1 | |
| SCHEMBL5971051 | 0.67 | — | — | |
| SCHEMBL3457185 | 0.66 | — | — | |
| SCHEMBL28175769 | 0.65 | GSK3B (0.36) | HPGDSNPY5R | |
| SCHEMBL5820674 | 0.65 | HPGDS (0.33) | HPGDSNPY5R | |
| SCHEMBL27992258 | 0.65 | SCN2A (0.55) | HPGDSNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1780922-A | Compositions and methods for the treatment of severe acute respiratory syndrome (SARS) | ISIS PHARMACEUTICALS INC (US) | 2006-05-31 | — | — | CN | disclosed |