Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PGD | P52209 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18327243 | 0.82 | CACNA2D1 (0.47) | GABRR1LMNACACNA2D1CACNB3CACNA1C | |
| SCHEMBL3338524 | 0.81 | LMNA (0.36) | LMNASMN1; SMN2PGDSLC22A6CYP1A2 | |
| SCHEMBL29130349 | 0.79 | SMN1; SMN2 (0.35) | LMNAADRA1ASMN1; SMN2PGDSLC22A6 | |
| SCHEMBL29130353 | 0.79 | SMN1; SMN2 (0.35) | LMNAADRA1ASMN1; SMN2PGDSLC22A6 | |
| SCHEMBL6540754 | 0.78 | — | — | |
| SCHEMBL1468931 | 0.77 | DNM1 (0.31) | ALDH1A1 | |
| SCHEMBL25098960 | 0.76 | LMNA (0.58) | LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL25098996 | 0.76 | LMNA (0.58) | LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL24342134 | 0.74 | — | — | |
| SCHEMBL2700221 | 0.74 | PGD (0.36) | GABRR1LMNACACNA2D1CACNB3CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100509766-C | Preparation method of chiral non alpha amino acid derivative simultaneously protected by hydroxyl group and amino group | WEN ZHANG (CN) | 2009-07-08 | — | — | CN | disclosed |
| CN-1869008-A | Preparation method of chiral non alpha amino acid derivative of simultaneously protected by hydroxyl group and amino group | ZHANG WEN (CN) | 2006-11-29 | — | — | CN | disclosed |