Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPOR | P19235 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 4/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | GNA15 | P30679 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230424 | 0.81 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2PTGESMAPT | |
| SCHEMBL27647851 | 0.78 | FOLH1 (0.34) | ALDH1A1 | |
| SCHEMBL27627640 | 0.76 | MLYCD (0.39) | FFAR1LMNA | |
| SCHEMBL11428311 | 0.68 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL1828040 | 0.66 | BCHE (0.70) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL27721942 | 0.65 | GRM2 (0.47) | FFAR1ALDH1A1CETPGRM2 | |
| SCHEMBL11252610 | 0.64 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL380050 | 0.64 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4704701 | 0.64 | ALDH1A1 (0.50) | ALDH1A1KDM4E | |
| SCHEMBL3199587 | 0.63 | MTNR1A (0.59) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101058564-A | Production of arylalkyl carbamate derivatives and their use in therapy | SANOFI AVENTIS (FR) | 2007-10-24 | — | — | CN | disclosed |
| CN-1741990-A | Production of arylalkyl carbamate derivatives and their use in therapy | SANOFI AVENTIS (FR) | 2006-03-01 | — | — | CN | disclosed |