Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.34 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27627640 | 0.85 | MLYCD (0.39) | TSHR | |
| SCHEMBL250872 | 0.76 | ALDH1A1 (0.52) | ALDH1A1GLATSHRMEN1KMT2A | |
| SCHEMBL250128 | 0.68 | ALOX5 (0.42) | ALDH1A1GLATSHRMEN1KMT2A | |
| SCHEMBL16606247 | 0.65 | ALDH1A1 (0.42) | ALDH1A1GLATSHRMEN1KMT2A | |
| SCHEMBL5218475 | 0.65 | TP53 (0.43) | ALDH1A1GLATSHRMEN1KMT2A | |
| SCHEMBL8342856 | 0.64 | ALDH1A1 (0.47) | ALDH1A1GLATSHRMEN1KMT2A | |
| SCHEMBL11037938 | 0.64 | ALDH1A1 (0.52) | ALDH1A1GLATSHRMEN1KMT2A | |
| SCHEMBL915703 | 0.64 | ALDH1A1 (0.52) | ALDH1A1GLATSHRMEN1KMT2A | |
| SCHEMBL27544700 | 0.63 | ALDH1A1 (0.46) | ALDH1A1GLATSHRMEN1KMT2A | |
| SCHEMBL5702149 | 0.62 | ALDH1A1 (0.53) | ALDH1A1GLATSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101058564-A | Production of arylalkyl carbamate derivatives and their use in therapy | SANOFI AVENTIS (FR) | 2007-10-24 | — | — | CN | disclosed |
| CN-1741990-A | Production of arylalkyl carbamate derivatives and their use in therapy | SANOFI AVENTIS (FR) | 2006-03-01 | — | — | CN | disclosed |