Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.56 |
| ▸ | ECE1 | P42892 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | CASP9 | P55211 | 1/20 | 0.56 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 4/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CTSK | P43235 | 4/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7624700 | 0.95 | FOLH1 (0.59) | MMEECE1CASP1FOLH1HTT | |
| SCHEMBL2921260 | 0.95 | FOLH1 (0.59) | MMEECE1CASP1FOLH1HTT | |
| SCHEMBL677997 | 0.95 | FOLH1 (0.59) | MMEECE1CASP1FOLH1HTT | |
| SCHEMBL9697579 | 0.92 | MME (0.65) | MMEECE1CASP1CASP3CASP7 | |
| SCHEMBL13884435 | 0.89 | MME (0.64) | MMEECE1CASP1CASP3CASP7 | |
| SCHEMBL1426719 | 0.89 | MME (0.64) | MMEECE1CASP1CASP3CASP7 | |
| SCHEMBL13957718 | 0.89 | MME (0.64) | MMEECE1CASP1CASP3CASP7 | |
| SCHEMBL4910765 | 0.88 | FOLH1 (0.58) | MMEECE1CASP1FOLH1HTT | |
| SCHEMBL10565196 | 0.88 | FOLH1 (0.58) | MMEECE1CASP1FOLH1HTT | |
| SCHEMBL6384215 | 0.88 | CTSL (0.66) | SIRT5CTSLCTSSCTSKTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105205-A1 | ANTIBODY-DRUG CONJUGATES (A2DCS) WITH ENZYMATICALLY CLEAVABLE GROUPS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-05-23 | — | — | WO | disclosed |