SCHEMBL27651122

SCHEMBL27651122

Cc1cc(C(=O)C2(Br)CCCCC2)ccc1CCBr

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 2/20 0.35
GNG2 P59768 1/20 0.34
GNB1 P62873 1/20 0.34
LMNA P02545 1/20 0.34
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33
RAB9A P51151 3/20 0.33
RXRA P19793 2/20 0.33
NPC1 O15118 1/20 0.33
HDAC6 Q9UBN7 1/20 0.32
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HPGD P15428 2/20 0.31
TSHR P16473 1/20 0.31
EPHX2 P34913 1/20 0.30
ALDH1A1 P00352 2/20 0.30
APOBEC3A P31941 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27651113 0.89 OPRM1 (0.36) GSK3BGNG2GNB1LMNAOPRM1
SCHEMBL3669453 0.89 LMNA (0.35) GSK3BGNG2GNB1LMNAOPRM1
SCHEMBL3672688 0.81 CES2 (0.42) LMNARAB9ANPC1MAPTSMN1; SMN2
SCHEMBL3671983 0.81 LMNA (0.35) GSK3BGNG2GNB1LMNAOPRM1
SCHEMBL3678900 0.79 OPRM1 (0.34) GSK3BLMNAOPRM1OPRD1SMN1; SMN2
SCHEMBL27311828 0.75 EPHX2 (0.49) GSK3BRXRASMN1; SMN2TSHREPHX2
SCHEMBL28761815 0.71 MAPT (0.48) LMNANPC1MAPTSMN1; SMN2HPGD
SCHEMBL27806590 0.71 MAPT (0.38) GSK3BLMNARAB9AMAPTHPGD
SCHEMBL3672637 0.70 KDM2B (0.35) LMNARAB9ARXRANPC1HDAC6
SCHEMBL3672849 0.69 KDM2B (0.36) RXRAHDAC6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100548955-C photoinitiator CIBA SC HOLDING AG (CH) 2009-10-14 CN disclosed
CN-1942424-A Novel photoinitiators CIBA SC HOLDING AG (CH) 2007-04-04 CN disclosed