Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31739258 | 0.88 | LTA4H (0.67) | LTA4HMAOBMTNR1AMTNR1BSIGMAR1 | |
| SCHEMBL2092574 | 0.88 | LTA4H (0.67) | LTA4HMAOBMTNR1AMTNR1BSIGMAR1 | |
| 1,3-Dimethoxybenzene SCHEMBL27963601 | 0.82 | MAOB (0.50) | MAOBMTNR1BTAAR1IDO1AGXT | |
| SCHEMBL2099512 | 0.82 | CHRM2 (0.66) | LTA4HMAOBSIGMAR1CHRM2CHRM1 | |
| Anisole SCHEMBL27631024 | 0.80 | CA4 (0.64) | LTA4HMAOBSIGMAR1 | |
| SCHEMBL8093299 | 0.80 | MTNR1A (0.57) | LTA4HMAOBMTNR1AMTNR1BSIGMAR1 | |
| SCHEMBL14191204 | 0.79 | LTA4H (0.70) | LTA4HMAOBMTNR1AMTNR1BCHRM2 | |
| SCHEMBL27651331 | 0.78 | CYP3A4 (0.53) | MAOB | |
| SCHEMBL6461595 | 0.78 | TAAR1 (0.55) | MAOBSIGMAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL8515510 | 0.77 | MTNR1A (0.58) | LTA4HMAOBMTNR1AMTNR1BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1771050-A | macrocyclic inhibitors of hepatitis c serine protease | ENANTA PHARM INC (US) | 2006-05-10 | — | — | CN | disclosed |