Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL209765 | 0.83 | ALDH1A1 (0.46) | MAPTALDH1A1MEN1PKMKMT2A | |
| SCHEMBL3414903 | 0.83 | ALDH1A1 (0.46) | MAPTALDH1A1MEN1PKMKMT2A | |
| SCHEMBL18209593 | 0.78 | ALDH1A1 (0.48) | MAPTALDH1A1ALOX15KMT2APOLB | |
| SCHEMBL212347 | 0.78 | ALDH1A1 (0.43) | MAPTALDH1A1ALOX15KMT2APOLB | |
| SCHEMBL209046 | 0.78 | ALDH1A1 (0.48) | MAPTALDH1A1ALOX15KMT2APOLB | |
| SCHEMBL24079397 | 0.76 | ALDH1A1 (0.52) | MAPTALDH1A1ALOX15KMT2APOLB | |
| SCHEMBL28719 | 0.76 | ALDH1A1 (0.52) | MAPTALDH1A1ALOX15KMT2APOLB | |
| SCHEMBL25434872 | 0.76 | ALDH1A1 (0.52) | MAPTALDH1A1ALOX15KMT2APOLB | |
| SCHEMBL20842702 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL20375020 | 0.76 | ALDH1A1 (0.52) | MAPTALDH1A1ALOX15KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
| US-12344623-B2 | Thiazolopyridine derivatives as adenosine receptor antagonists | DOMAIN THERAPEUTICS SA (FR) | 2025-07-01 | — | — | US | disclosed |
| US-20220119412-A1 | THIAZOLOPYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2022-04-21 | — | — | US | disclosed |
| CN-1902180-B | Use of 4-cyano-naphthalene-1, 8-dicarboximide derivatives and related compounds for protecting organic materials from the damaging effects of light | BASF AG | 2010-08-25 | — | — | CN | disclosed |
| CN-1902180-A | Use of 4-cyano-naphthalene-1, 8-dicarboximide derivatives and related compounds for protecting organic materials from the damaging effects of light | BASF AG (DE) | 2007-01-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12344623-B2 | Thiazolopyridine derivatives as adenosine receptor antagonists | ADORA1, ADORA2A, ADORA3 | MAPT 4012/4885ALDH1A1 233/4885MEN1 2872/4885 |
| US-20220119412-A1 | THIAZOLOPYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | ADORA1, ADORA2A, ADORA3 | MAPT 4012/4885ALDH1A1 233/4885MEN1 2872/4885 |
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | MAPT 4709/4885ALDH1A1 3714/4885MEN1 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.