Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28077552 | 0.79 | MAOA (0.37) | IDO1MAOAMAOB | |
| SCHEMBL29114120 | 0.76 | NOX1 (0.42) | MAOAMAOBNOX1GAAMEN1 | |
| SCHEMBL6927126 | 0.76 | LMNA (0.42) | NOX1MEN1MAPTKMT2A | |
| SCHEMBL27508187 | 0.75 | PGR (0.47) | — | |
| SCHEMBL18885231 | 0.74 | IDO1 (0.52) | IDO1MAOANOX1BCHEACHE | |
| SCHEMBL31564905 | 0.74 | IDO1 (0.52) | IDO1MAOANOX1BCHEACHE | |
| SCHEMBL22791825 | 0.73 | IDO1 (0.62) | IDO1MAOAMAOBCES1NOX1 | |
| SCHEMBL16542426 | 0.73 | IDO1 (0.62) | IDO1MAOAMAOBCES1NOX1 | |
| SCHEMBL22000385 | 0.69 | IDO1 (0.57) | IDO1MAOAMAOBNOX1BCHE | |
| SCHEMBL28246279 | 0.69 | NOX1 (0.38) | MAOAMAOBNOX1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101516889-B | Derivatives and analogs of n-ethylquinolones and n-ethylazaquinolones | GLAXO GROUP LTD | 2013-07-31 | — | — | CN | disclosed |
| CN-102329267-A | 6-substituted 2,3,4, 5-tetrahydro-1H-benzo [d] aza as 5-HT2Creceptor agonists | LILLY CO ELI | 2012-01-25 | — | — | CN | disclosed |
| CN-102311387-A | 6-substituted 2,3,4, 5-tetrahydro-1H-benzo [d] aza as 5-HT2Creceptor agonists | LILLY CO ELI | 2012-01-11 | — | — | CN | disclosed |
| CN-102272112-A | Benzothiazolone Derivatives | — | 2011-12-07 | — | — | CN | disclosed |
| CN-101516378-B | Morpholinyl and pyrrolidinyl analogs | SMITHKLINE BEECHAM CORP | 2011-06-15 | — | — | CN | disclosed |
| CN-101516889-A | Derivatives and analogs of n-ethylquinolones and n-ethylazaquinolones | GLAXO GROUP LTD (GB) | 2009-08-26 | — | — | CN | disclosed |
| CN-101516378-A | Morpholinyl and pyrrolidinyl analogs | SMITHKLINE BEECHAM CORP (US) | 2009-08-26 | — | — | CN | disclosed |
| CN-101189218-A | Benzothiazol-2-on derivatives as lipase and phospholipase inhibitors | SANOFI AVENTIS (FR) | 2008-05-28 | — | — | CN | disclosed |
| CN-1934088-A | As 5-HT2c6-substituted 2,3,4, 5-tetrahydro-1H-benzo [ d ] receptor agonists]Aza * | LILLY CO ELI (US) | 2007-03-21 | — | — | CN | disclosed |