Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27507927 | 0.79 | CA9 (0.31) | CA9 | |
| SCHEMBL27704528 | 0.79 | TGM2 (0.40) | CA12CA1CA2CA4CA7 | |
| SCHEMBL18885231 | 0.74 | IDO1 (0.52) | NOX1MAPTCYP1A2ALDH1A1POLB | |
| SCHEMBL27508187 | 0.72 | PGR (0.47) | KDM4E | |
| SCHEMBL27741244 | 0.72 | PDE4A (0.33) | — | |
| SCHEMBL27589795 | 0.71 | ESR2 (0.41) | — | |
| SCHEMBL27741245 | 0.71 | RAF1 (0.40) | POLBMAOBKMT2A | |
| SCHEMBL24695997 | 0.69 | NOX1 (0.38) | NOX1 | |
| SCHEMBL28077552 | 0.69 | MAOA (0.37) | POLBMAOAMAOB | |
| SCHEMBL27652137 | 0.69 | IDO1 (0.57) | NOX1MAPTGAAMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602770-A | Novel biphenol compound or its salt | 大鹏药品工业株式会社 | 2018-09-28 | — | — | CN | disclosed |