Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.55 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalamide SCHEMBL7508921 | 0.89 | PARP10 (0.67) | PARP1MAPTPOLBCYP3A4TSHR | |
| Benzamide SCHEMBL28263471 | 0.88 | PARP1 (0.67) | PARP1MAPTPOLBCYP3A4TSHR | |
| Benzamide SCHEMBL2401802 | 0.85 | PARP1 (0.76) | PARP1MAPTPOLBCYP3A4TSHR | |
| Benzamide SCHEMBL1637053 | 0.85 | PARP1 (0.76) | PARP1MAPTPOLBCYP3A4TSHR | |
| Ether SCHEMBL9388847 | 0.84 | CES2 (0.52) | PARP1MAPTPOLBCYP3A4TSHR | |
| Benzoic Acid SCHEMBL931656 | 0.83 | TSHR (0.64) | MAPTPOLBTSHRMEN1KMT2A | |
| Benzamide SCHEMBL9496452 | 0.83 | PARP1 (0.73) | PARP1MAPTPOLBCYP3A4TSHR | |
| Benzophenone SCHEMBL1147390 | 0.83 | ALDH1A1 (0.64) | MAPTTDP1L3MBTL1MEN1KMT2A | |
| Benzophenone SCHEMBL1147611 | 0.83 | ALDH1A1 (0.64) | MAPTTDP1L3MBTL1MEN1KMT2A | |
| Benzamide SCHEMBL11654359 | 0.83 | PARP1 (0.73) | PARP1MAPTPOLBCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1091420-A | Process for the preparation of diphenylamine derivatives | YONGXIN MEDICINES AND CHEMICAL (CN) | 1994-08-31 | — | — | CN | claimed |
| EP-2046747-A1 | SUBSTITUTED AMINOMETHYL BENZAMIDE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-04-15 | — | — | EP | disclosed |
| US-20080045508-A1 | SUBSTITUTED AMINOMETHYL BENZAMIDE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-02-21 | — | — | US | disclosed |
| WO-2008002818-A1 | SUBSTITUTED AMINOMETHYL BENZAMIDE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-01-03 | — | — | WO | disclosed |
| CN-1105100-C | Compounds with anti-inflammatory and immunosuppressive activity | ITALFARMACO SPA (IT) | 2003-04-09 | — | — | CN | disclosed |
| CN-1221403-A | Compounds with anti-inflammatory and immunosuppressive activity | ITALFARMACO SPA (IT) | 1999-06-30 | — | — | CN | disclosed |
| CN-1091420-A | Process for the preparation of diphenylamine derivatives | YONGXIN MEDICINES AND CHEMICAL (CN) | 1994-08-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045508-A1 | SUBSTITUTED AMINOMETHYL BENZAMIDE COMPOUNDS | HNMT, HRH3, HRH4 | PARP1 1748/4885MAPT 1233/4885POLB 4118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.