Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31287985 | 1.00 | MEP1B (0.41) | MEP1BMAPTPDE4APDE4BPDE4C | |
| SCHEMBL8470910 | 0.84 | MEP1B (0.51) | MEP1BMAPTPDE4APDE4BPDE4C | |
| SCHEMBL23286528 | 0.82 | CA2 (0.38) | MEP1BMAPTPDE4APDE4BPDE4C | |
| SCHEMBL4435401 | 0.82 | MAPT (0.37) | MEP1BMAPTPDE4APDE4BPDE4C | |
| SCHEMBL14948906 | 0.82 | MEP1B (0.42) | MEP1BALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL27471219 | 0.81 | MEP1B (0.43) | MEP1BMAPTPDE4APDE4BPDE4C | |
| SCHEMBL8134900 | 0.81 | MEP1B (0.39) | MEP1BMAPTPDE4APDE4BPDE4C | |
| SCHEMBL4592472 | 0.80 | MEP1B (0.41) | MEP1BMAPTALDH1A1HTR2AHTR2C | |
| SCHEMBL13548303 | 0.78 | HMGCR (0.39) | MEP1BALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL24780447 | 0.78 | MEP1B (0.43) | MEP1BKDM4ECD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1914173-A | Quinolines useful in treating cardiovascular disease | WYETH CORP (US) | 2007-02-14 | — | — | CN | disclosed |