Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592694 | 0.84 | MEP1B (0.51) | MEP1BHTR2AHTR2CHTR2BCYP19A1 | |
| SCHEMBL14948906 | 0.82 | MEP1B (0.42) | MEP1BHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL13548296 | 0.81 | ALOX5AP (0.37) | MEP1B | |
| SCHEMBL27654036 | 0.80 | MEP1B (0.41) | MEP1BHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL31287985 | 0.80 | MEP1B (0.41) | MEP1BHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL13548303 | 0.78 | HMGCR (0.39) | MEP1BHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL13547904 | 0.77 | ALOX5AP (0.36) | MEP1BHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL8134900 | 0.77 | MEP1B (0.39) | MEP1BALDH1A1MAPT | |
| SCHEMBL19814847 | 0.76 | SLC6A2 (0.43) | MEP1BALDH1A1MAPT | |
| SCHEMBL4592925 | 0.76 | PTGS2 (0.32) | MEP1BHTR2AHTR2CHTR2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957232-B | Benzodihydro oxazine compound, preparation method thereof and anti-tuberculosis application | 四川大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-114957232-A | Benzo-dihydro-oxazine compound, preparation method thereof and anti-tuberculosis application thereof | 四川大学 | 2022-08-30 | — | — | CN | disclosed |
| EP-1807398-B1 | NEW INDOLE OR BENZIMIDAZOLE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-06-25 | — | — | EP | disclosed |