Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27613758 | 0.89 | ESR2 (0.36) | ESR2 | |
| SCHEMBL5311531 | 0.84 | ESR2 (0.32) | ESR2 | |
| SCHEMBL1636292 | 0.80 | CRHR1 (0.39) | ESR2 | |
| SCHEMBL1762452 | 0.79 | CYP1A2 (0.32) | ESR2 | |
| SCHEMBL1505411 | 0.67 | ALDH1A1 (0.39) | — | |
| SCHEMBL2537872 | 0.64 | ALDH1A1 (0.34) | ESR2 | |
| SCHEMBL27613787 | 0.64 | FPR3 (0.33) | — | |
| SCHEMBL1645423 | 0.63 | CA1 (0.41) | — | |
| SCHEMBL14240535 | 0.62 | DRD2 (0.38) | ESR2 | |
| SCHEMBL18188355 | 0.62 | S1PR4 (0.38) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1972941-A | Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with tetrahydropyridine as CRF antagonists | TAISHO PHARMACEUTICAL CO LTD (JP) | 2007-05-30 | — | — | CN | disclosed |