Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883625 | 0.82 | S100A4 (0.40) | MAPTPOLBAPEX1CASP6KMT2A | |
| SCHEMBL27655697 | 0.76 | AAK1 (0.40) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28763126 | 0.74 | ALDH1A1 (0.48) | MAPTPOLBAPEX1CASP6KMT2A | |
| SCHEMBL30774912 | 0.72 | GPR35 (0.42) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL690072 | 0.72 | GPR35 (0.42) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5707256 | 0.70 | ALDH1A1 (0.59) | MAPTPOLBAPEX1CASP6KMT2A | |
| SCHEMBL27651637 | 0.70 | KMT2A (0.45) | MAPTPOLBAPEX1CASP6KMT2A | |
| SCHEMBL3476440 | 0.69 | MAPT (0.59) | MAPTPOLBAPEX1CASP6KMT2A | |
| SCHEMBL30997911 | 0.68 | MEN1 (0.40) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30991375 | 0.68 | MAPT (0.50) | MAPTPOLBAPEX1CASP6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1933834-A | Use of indazolecarboxamide derivatives for the preparation of a medicament for the treatment and prevention of malaria | SANOFI AVENTIS (FR) | 2007-03-21 | — | — | CN | disclosed |