Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27655698 | 0.76 | MAPT (0.43) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL30774912 | 0.74 | GPR35 (0.42) | AAK1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL690072 | 0.74 | GPR35 (0.42) | AAK1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL5528639 | 0.72 | BACE1 (0.38) | MEN1KMT2AMAPTMAPK1GAA | |
| SCHEMBL6059124 | 0.72 | CASP6 (0.47) | TSHRALDH1A1LMNA | |
| SCHEMBL28763125 | 0.71 | RPS6KA3 (0.58) | MEN1KMT2AMAPTMAPK1GAA | |
| SCHEMBL27769709 | 0.71 | ALK (0.41) | MEN1KMT2AMAPTMAPK1GAA | |
| SCHEMBL27376059 | 0.71 | GPR35 (0.57) | MEN1KMT2AMAPTMAPK1GAA | |
| SCHEMBL30997911 | 0.70 | MEN1 (0.40) | AAK1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL28883625 | 0.70 | S100A4 (0.40) | AAK1MEN1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1933834-A | Use of indazolecarboxamide derivatives for the preparation of a medicament for the treatment and prevention of malaria | SANOFI AVENTIS (FR) | 2007-03-21 | — | — | CN | disclosed |