Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27719617 | 0.83 | L3MBTL1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL28270162 | 0.80 | AKR1C3 (0.41) | — | |
| SCHEMBL28038733 | 0.78 | CES2 (0.41) | — | |
| SCHEMBL14632077 | 0.77 | AOC3 (0.43) | HTT | |
| SCHEMBL14632079 | 0.77 | AOC3 (0.43) | HTT | |
| SCHEMBL28270160 | 0.77 | AKR1C3 (0.40) | — | |
| SCHEMBL29888871 | 0.76 | PDE2A (0.34) | — | |
| SCHEMBL19480805 | 0.73 | ESR1 (0.40) | ALDH1A1LMNA | |
| SCHEMBL27655952 | 0.73 | — | — | |
| SCHEMBL28857685 | 0.72 | CYP2C19 (0.47) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1946397-A | Ion channel modulators | SCION PHARMACEUTICALS INC (US) | 2007-04-11 | — | — | CN | disclosed |
| CN-1938020-A | Ion channel modulators | SCION PHARMACEUTICALS INC (US) | 2007-03-28 | — | — | CN | disclosed |
| CN-1930132-A | Ion channel modulators | WYETH CORP (US) | 2007-03-14 | — | — | CN | disclosed |