Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10861357 | 0.78 | GABRA1 (0.44) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL1123893 | 0.75 | ALB (0.46) | ALBALDH1A1MAPTSMN1; SMN2DYRK1A | |
| SCHEMBL31371878 | 0.72 | LCK (0.51) | ALDH1A1MAPTSMN1; SMN2DYRK1AKDM4E | |
| SCHEMBL7706331 | 0.72 | LCK (0.51) | ALDH1A1MAPTSMN1; SMN2DYRK1AKDM4E | |
| SCHEMBL8645930 | 0.71 | ALDH1A1 (0.50) | ALBALDH1A1MAPTSMN1; SMN2DYRK1A | |
| SCHEMBL27260256 | 0.70 | ALB (0.41) | ALBPARP1CES2CES1MEN1 | |
| SCHEMBL27032773 | 0.66 | PARP1 (0.41) | ALBALDH1A1PARP1TTRMGAM | |
| SCHEMBL3328166 | 0.66 | MGAM (0.42) | ALBALDH1A1PARP1KDM4EMGAM | |
| SCHEMBL20839321 | 0.65 | TTR (0.34) | KDM4ETTRAKR1C2AKR1C1 | |
| SCHEMBL2437553 | 0.64 | KDM4E (0.42) | ALBALDH1A1MAPTSMN1; SMN2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100471842-C | Carbostyril derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-03-25 | — | — | CN | disclosed |
| CN-1826321-A | Quinolone derivative or its salt | YAMANOUCHI PHARMA CO LTD (JP) | 2006-08-30 | — | — | CN | disclosed |