Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | PHGDH | O43175 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27656560 | 1.00 | LMNA (0.64) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31546660 | 0.86 | LMNA (0.63) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28257375 | 0.85 | LMNA (0.61) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31546635 | 0.84 | ALDH1A1 (0.64) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10768107 | 0.80 | NPC1 (0.65) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10763115 | 0.80 | NPC1 (0.65) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10763104 | 0.80 | NPC1 (0.65) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27876824 | 0.79 | LMNA (0.64) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27876821 | 0.79 | LMNA (0.64) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31546622 | 0.79 | ALDH1A1 (0.63) | LMNAMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1944398-A | New benzoyl amide compounds and its preparing method and medicine use | INST OF MEDICINES CHINESE ACAD (CN) | 2007-04-11 | — | — | CN | disclosed |