Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PHGDH | O43175 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31546661 | 0.89 | KMT2A (0.51) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27656560 | 0.86 | LMNA (0.64) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27656657 | 0.86 | LMNA (0.64) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28257375 | 0.84 | LMNA (0.61) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31546635 | 0.83 | ALDH1A1 (0.64) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31546624 | 0.80 | LMNA (0.54) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10763104 | 0.79 | NPC1 (0.65) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10763115 | 0.79 | NPC1 (0.65) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10768107 | 0.79 | NPC1 (0.65) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27876824 | 0.78 | LMNA (0.64) | LMNAMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119899184-A | Beta-carboline compound, preparation method thereof and application thereof in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2025-04-29 | — | — | CN | disclosed |