Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | CASP3 | P42574 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.69 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.69 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.66 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.66 |
| ▸ | KCNMA1 | Q12791 | 6/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PHGDH | O43175 | 1/20 | 0.56 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752705 | 0.85 | HCAR3 (0.74) | HCAR3NPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL10334186 | 0.85 | KCNMA1 (0.66) | HCAR3NPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL14402986 | 0.84 | HCAR3 (0.72) | HCAR3NPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL30739620 | 0.84 | HCAR3 (0.72) | HCAR3NPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL11147988 | 0.84 | HCAR3 (0.72) | HCAR3NPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL7597875 | 0.83 | HCAR3 (0.80) | HCAR3NPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL641989 | 0.83 | PHGDH (0.77) | HCAR3NPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL30739928 | 0.79 | HCAR3 (0.66) | HCAR3NPC1RAB9AMAPK1ALDH1A1 | |
| Acetic Acid SCHEMBL27684276 | 0.79 | MAPT (0.62) | HCAR3NPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL694246 | 0.78 | NPSR1 (0.66) | HCAR3ALDH1A1HTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1966495-B | Method for preparing 5-(4- fluobenzene sulphonyloxy) benzimidazole-2-amido methyl formate | CHANGZHOU YABANG QIHUI FINE CHEMICALS CO LTD | 2010-06-16 | — | — | CN | disclosed |
| CN-1966495-A | Method for preparing 5-(4- fluobenzene sulphonyloxy) benzimidazole-2-amido methyl formate | CHANGZHOU YABANG QIHUI FINE CH (CN) | 2007-05-23 | — | — | CN | disclosed |