SCHEMBL27657682

SCHEMBL27657682

COC(=O)c1cc(Oc2cccc(O)c2)ccc1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPSE Q9Y251 1/20 0.51
POLB P06746 2/20 0.50
KDM4E B2RXH2 1/20 0.50
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA7 P43166 2/20 0.47
CA9 Q16790 2/20 0.47
CA14 Q9ULX7 2/20 0.47
PDK2 Q15119 1/20 0.47
PDK4 Q16654 1/20 0.47
TDP1 Q9NUW8 4/20 0.47
PTPN11 Q06124 2/20 0.47
DUSP3 P51452 1/20 0.47
PTPN5 P54829 1/20 0.47
AKR1C3 P42330 1/20 0.47
AKR1C2 P52895 1/20 0.47
GALK1 P51570 1/20 0.46
CASP6 P55212 1/20 0.46
MCL1 Q07820 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22441922 0.88 POLB (0.60) HPSEPOLBKDM4ETDP1AKR1C3
SCHEMBL11576384 0.88 POLB (0.54) HPSEPOLBKDM4ECA12CA1
SCHEMBL11574967 0.85 POLB (0.55) HPSEPOLBKDM4ECA12CA1
SCHEMBL8008958 0.85 POLB (0.55) HPSEPOLBKDM4ECA12CA1
Resorcinol SCHEMBL9393557 0.83 POLB (0.61) HPSEPOLBKDM4ECA12CA1
SCHEMBL8541373 0.83 POLB (0.57) HPSEPOLBKDM4ECA12CA1
SCHEMBL22441920 0.82 POLB (0.60) HPSEPOLBKDM4ETDP1AKR1C3
SCHEMBL7765911 0.82 XDH (0.55) POLBKDM4ETDP1AKR1C3ALDH1A1
SCHEMBL8008956 0.81 POLB (0.54) HPSEPOLBKDM4ECA12CA1
SCHEMBL27558985 0.80 CA12 (0.67) POLBKDM4ECA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100443464-C AB type dibasic aminoacid monomer containing hydroxy group and its preparation method UNIV SICHUAN (CN) 2008-12-17 CN disclosed
CN-1865225-A AB type dibasic aminoacid monomer containing hydroxy group and its preparation method UNIV SICHUAN (CN) 2006-11-22 CN disclosed