SCHEMBL8008958

SCHEMBL8008958

COC(=O)c1ccc(Oc2ccc(C(=O)O)c(C(=O)O)c2)cc1C(=O)OC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.55
ALDH1A1 P00352 1/20 0.54
HPSE Q9Y251 1/20 0.51
TDP1 Q9NUW8 4/20 0.50
LMNA P02545 1/20 0.47
KDM4E B2RXH2 2/20 0.46
GALK1 P51570 1/20 0.46
CASP6 P55212 1/20 0.46
MCL1 Q07820 1/20 0.46
PLEC Q15149 1/20 0.46
PYGM P11217 4/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
PYGL P06737 4/20 0.45
DUSP3 P51452 1/20 0.44
PTPN5 P54829 1/20 0.44
PTPN11 Q06124 1/20 0.44
APEX1 P27695 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11574967 1.00 POLB (0.55) POLBALDH1A1HPSETDP1LMNA
SCHEMBL8541373 0.98 POLB (0.57) POLBALDH1A1HPSETDP1LMNA
SCHEMBL11576384 0.96 POLB (0.54) POLBALDH1A1HPSETDP1LMNA
SCHEMBL8008956 0.96 POLB (0.54) POLBALDH1A1HPSETDP1LMNA
SCHEMBL9550314 0.91 KDM4E (0.51) POLBALDH1A1TDP1LMNAKDM4E
SCHEMBL22441920 0.90 POLB (0.60) POLBALDH1A1HPSETDP1LMNA
SCHEMBL22441922 0.90 POLB (0.60) POLBALDH1A1HPSETDP1LMNA
SCHEMBL7765911 0.86 XDH (0.55) POLBALDH1A1TDP1LMNAKDM4E
SCHEMBL1956889 0.86 KDM4E (0.60) POLBALDH1A1LMNAKDM4ECYP1A2
SCHEMBL5736385 0.86 KDM4E (0.60) POLBALDH1A1LMNAKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107082881-B Synthetic method and application of semi-aromatic polyimide 株洲时代新材料科技股份有限公司 2020-02-11 CN disclosed
US-6133407-A LOW VISCOSITY SOLUTION CONTAINING HIGH CONCENTRATION OF SALT OF AROMATIC DIAMINE AND AROMATIC TETRACARBOXYLIC ACID AND/OR ITS DIESTER WHICH UNDERGOES IMIDATION UPON HEATING UNITKA LTD. (JP) 2000-10-17 US disclosed
EP-0887364-A2 Polyimide precursor solution, coating film obtained therefrom, and process for producing polyimide coating film UNITIKA LTD. (JP) 1998-12-30 EP disclosed
EP-0248932-B1 PROCESS FOR PREPARING POLYAMIDES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-01-09 EP disclosed
EP-0177793-B1 PROCESS FOR PREPARING POLYAMIDES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1990-11-28 EP disclosed
US-4754016-A Process for preparing polyamide with organic phosphine/organic disulfide mixture condensing agent ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-06-28 US disclosed
EP-0248932-A1 Process for preparing polyamides Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-12-16 EP disclosed
US-4645823-A CORROSION RESISTANCE; NONTOXIC ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1987-02-24 US disclosed
EP-0177793-A2 Process for preparing polyamides Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-04-16 EP disclosed