Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.39 |
| ▸ | HTR1A | P08908 | 6/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | QDPR | P09417 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075115 | 0.87 | PTGS1 (0.31) | — | |
| SCHEMBL9730874 | 0.83 | PTGDR2 (0.33) | — | |
| SCHEMBL19595794 | 0.83 | ABCC8 (0.31) | — | |
| SCHEMBL7838303 | 0.81 | PTGDR2 (0.35) | HTR2C | |
| SCHEMBL433060 | 0.81 | PTGDR2 (0.35) | HTR2C | |
| SCHEMBL2097686 | 0.80 | QDPR (0.49) | SLC18A3SIGMAR1HTR2CQDPRHTR6 | |
| SCHEMBL3764985 | 0.79 | ESR2 (0.36) | — | |
| SCHEMBL5106428 | 0.79 | HTR3A (0.41) | SLC6A2SLC6A4SLC6A3HTR1ASLC18A3 | |
| SCHEMBL8558191 | 0.79 | HTR2C (0.50) | SLC6A2SLC6A4SLC6A3HTR1ASLC18A3 | |
| SCHEMBL3770026 | 0.79 | ESR2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1972911-A | 2-(1h-indolylsulfanyl)-aryl amine derivatives for use in the treatment of affective disorders, pain, adhd and stress urinary incontinence | LUNDBECK & CO AS H (DK) | 2007-05-30 | — | — | CN | disclosed |