Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2765063 | 0.96 | MAPT (0.45) | MAPTHTR7KDM4EALDH1A1TDP1 | |
| SCHEMBL2766897 | 0.92 | MAPT (0.46) | MAPTHTR7KDM4EALDH1A1TDP1 | |
| SCHEMBL2765386 | 0.89 | SLC29A1 (0.46) | MAPTHTR7KDM4EALDH1A1TDP1 | |
| SCHEMBL2766572 | 0.86 | HTR7 (0.61) | HTR7KDM4EALDH1A1TDP1GAA | |
| SCHEMBL2765186 | 0.83 | HTR7 (0.57) | HTR7KDM4EALDH1A1TDP1ABCB1 | |
| SCHEMBL2764078 | 0.82 | MAPT (0.53) | MAPTKDM4EALDH1A1TDP1GAA | |
| SCHEMBL2764871 | 0.80 | MAPT (0.51) | MAPTKDM4EALDH1A1TDP1GAA | |
| SCHEMBL2764643 | 0.79 | KDM4E (0.70) | MAPTHTR7KDM4EALDH1A1TDP1 | |
| SCHEMBL2763969 | 0.79 | ALDH1A1 (0.52) | MAPTKDM4EALDH1A1TDP1GAA | |
| SCHEMBL12718076 | 0.77 | KDM4E (0.48) | MAPTHTR7KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1400515-B1 | CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP | KOWA CO (JP) | 2010-04-14 | — | — | EP | disclosed |
| EP-1400515-A1 | CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP | Kowa Co., Ltd. (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6472386-B1 | Cyclic diamine compound with 5-membered ring groups | KOWA CO., LTD. (JP) | 2002-10-29 | — | — | US | disclosed |