SCHEMBL27658477

SCHEMBL27658477

CCC(CCC=O)Oc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AOX1 Q06278 1/20 0.41
PPARG P37231 3/20 0.37
PPARA Q07869 3/20 0.37
SLC6A4 P31645 1/20 0.36
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.34
ADRA2A P08913 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
NISCH Q9Y2I1 1/20 0.34
MAPT P10636 1/20 0.34
CTSL P07711 1/20 0.34
CTSB P07858 1/20 0.34
CTSK P43235 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1455125 0.84 SLC6A4 (0.37) PPARGPPARASLC6A4MTNR1AMTNR1B
SCHEMBL11065085 0.80 PPARG (0.44) PPARGPPARASLC6A4MTNR1AMTNR1B
SCHEMBL7034651 0.79 MTNR1A (0.35) PPARGPPARAMTNR1AMTNR1BTSHR
SCHEMBL7960172 0.79 TSHR (0.42) PPARGPPARASLC6A4MTNR1AMTNR1B
SCHEMBL1455116 0.78 SLC6A4 (0.35) PPARGPPARASLC6A4MTNR1AMTNR1B
SCHEMBL1454451 0.77 SLC7A5 (0.36) PPARGPPARASLC6A4TSHRALDH1A1
SCHEMBL27438936 0.77 LTA4H (0.44) PPARGPPARASLC6A4ALDH1A1CTSL
SCHEMBL5323618 0.77 SLC7A5 (0.43) PPARGPPARASLC6A4ALDH1A1
SCHEMBL10933718 0.77 SLC6A4 (0.39) PPARGPPARASLC6A4MTNR1AMTNR1B
SCHEMBL20169585 0.77 SLC6A4 (0.39) PPARGPPARASLC6A4MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1863756-A Preparation method of 4-hydroxydiphenyl ether SUMITOMO CHEMICAL CO (JP) 2006-11-15 CN disclosed