Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2767187 | 0.82 | NPSR1 (0.54) | NPSR1LMNASMN1; SMN2HTTPOLB | |
| SCHEMBL2769068 | 0.79 | ALDH1A1 (0.71) | LMNASMN1; SMN2HTTPOLBALDH1A1 | |
| SCHEMBL2768346 | 0.77 | LMNA (0.60) | NPSR1LMNASMN1; SMN2HTTPOLB | |
| SCHEMBL2768604 | 0.71 | KDM4E (0.48) | LMNASMN1; SMN2HTTPOLBALDH1A1 | |
| SCHEMBL2769245 | 0.70 | FFAR4 (0.49) | LMNASMN1; SMN2HTTALDH1A1KMT2A | |
| SCHEMBL4951517 | 0.70 | FFAR4 (0.39) | LMNASMN1; SMN2HTTPOLBALDH1A1 | |
| SCHEMBL2767962 | 0.70 | KDM4E (0.49) | LMNASMN1; SMN2HTTPOLBALDH1A1 | |
| SCHEMBL2767708 | 0.70 | L3MBTL1 (0.53) | LMNASMN1; SMN2HTTPOLBALDH1A1 | |
| SCHEMBL15188835 | 0.69 | KMT2A (0.67) | NPSR1LMNAHTTALDH1A1KMT2A | |
| SCHEMBL2766363 | 0.68 | HTR3E (0.54) | LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627871-B1 | CYCLIC AMINOPHENYL SULFAMATE DERIVATIVE | ASKA PHARM CO LTD (JP) | 2010-04-14 | — | — | EP | disclosed |