Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4573059 | 0.84 | HTR3A (0.48) | BRPF1BRD4LMNAALDH1A1DRD2 | |
| SCHEMBL25407029 | 0.82 | DRD2 (0.64) | BRPF1BRD4LMNAALDH1A1DRD2 | |
| SCHEMBL27680822 | 0.82 | DRD2 (0.64) | BRPF1BRD4LMNAALDH1A1DRD2 | |
| SCHEMBL14922244 | 0.82 | ALDH1A1 (0.48) | BRPF1BRD4LMNAALDH1A1HTR2C | |
| SCHEMBL21358963 | 0.81 | LMNA (0.47) | LMNAALDH1A1DRD2DRD4HTR3E | |
| SCHEMBL30952471 | 0.81 | LMNA (0.47) | LMNAALDH1A1DRD2DRD4HTR3E | |
| SCHEMBL30952442 | 0.81 | LMNA (0.47) | LMNAALDH1A1DRD2DRD4HTR3E | |
| SCHEMBL21358968 | 0.81 | LMNA (0.47) | LMNAALDH1A1DRD2DRD4HTR3E | |
| SCHEMBL21358964 | 0.81 | LMNA (0.47) | LMNAALDH1A1DRD2DRD4HTR3E | |
| SCHEMBL1904404 | 0.81 | ALDH1A1 (0.60) | BRPF1BRD4LMNAALDH1A1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1989106-A | N-hydroxyamide derivatives and their use | APPLIED RESEARCH SYSTEMS (AN) | 2007-06-27 | — | — | CN | claimed |
| CN-1989106-A | N-hydroxyamide derivatives and their use | APPLIED RESEARCH SYSTEMS (AN) | 2007-06-27 | — | — | CN | disclosed |