⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phorone SCHEMBL157728 | 0.82 | LMNA (0.39) | — | |
| Phorone SCHEMBL23856063 | 0.82 | LMNA (0.39) | — | |
| SCHEMBL28874243 | 0.79 | ALDH1A1 (0.30) | — | |
| Phorone SCHEMBL28899536 | 0.79 | LMNA (0.36) | — | |
| Phorone SCHEMBL27801489 | 0.79 | LMNA (0.36) | — | |
| Phorone SCHEMBL5084762 | 0.79 | LMNA (0.36) | — | |
| Phorone SCHEMBL30396963 | 0.79 | LMNA (0.36) | — | |
| Phorone SCHEMBL32672539 | 0.79 | LMNA (0.36) | — | |
| SCHEMBL4708068 | 0.75 | — | — | |
| SCHEMBL4708067 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1863778-A | Compounds and methods for treating dyslipidemia | LILLY CO ELI (US) | 2006-11-15 | — | — | CN | disclosed |