Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSCN1 | Q16658 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.38 |
| ▸ | TSPO | P30536 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2524320 | 0.83 | RIPK1 (0.41) | DPP4DPP9DPP8DPP7RIPK1 | |
| SCHEMBL20766756 | 0.79 | MPO (0.41) | RIPK1MPOIKBKB | |
| SCHEMBL14048382 | 0.78 | KEAP1 (0.46) | FSCN1DPP4DPP9DPP8DPP7 | |
| SCHEMBL14115782 | 0.76 | TSPO (0.47) | FSCN1DPP4TSPOPOLQHTT | |
| SCHEMBL24260342 | 0.75 | FSCN1 (0.39) | FSCN1TSPO | |
| SCHEMBL7002940 | 0.74 | FSCN1 (0.49) | FSCN1RIPK1TSPOHTT | |
| SCHEMBL19527708 | 0.73 | HRH4 (0.41) | FSCN1DPP4DPP9DPP8DPP7 | |
| SCHEMBL11933652 | 0.73 | KEAP1 (0.43) | DPP4DPP9DPP8DPP7RIPK1 | |
| SCHEMBL14067847 | 0.72 | KMT2A (0.40) | DPP9DPP8RIPK1MAOBMPO | |
| Hydrochloric Acid SCHEMBL4772671 | 0.71 | KMT2A (0.39) | RIPK1MPOHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1989141-B | Bicyclic heterocycles as HIV integrase inhibitors | BRISTOL MYERS SQUIBB CO | 2010-06-16 | — | — | CN | disclosed |
| CN-1989141-A | Bicyclic heterocycles as HIV integrase inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2007-06-27 | — | — | CN | disclosed |