Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KRAS | P01116 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680653 | 0.83 | HTT (0.65) | ALOX15HTTCA12CA1CA2 | |
| SCHEMBL30159674 | 0.83 | HTT (0.65) | ALOX15HTTCA12CA1CA2 | |
| SCHEMBL1285527 | 0.81 | ALOX15 (0.71) | ALOX15HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31429017 | 0.79 | MEN1 (0.51) | ALOX15HTTGABRA1GABRG2GABRB3 | |
| SCHEMBL4166286 | 0.79 | CA12 (0.51) | CA12CA1CA2CA9CA14 | |
| SCHEMBL8390404 | 0.78 | GABRA1 (0.50) | ALOX15GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL4987847 | 0.78 | NCF1 (0.46) | ALOX15HTTGABRA1GABRG2GABRB3 | |
| SCHEMBL27514811 | 0.76 | ALDH1A1 (0.56) | ALOX15HTTGABRA1GABRG2GABRB3 | |
| SCHEMBL4353066 | 0.76 | CYP19A1 (0.47) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL539883 | 0.76 | CYP19A1 (0.44) | GABRA1GABRG2GABRB3GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1950085-A | 3- (4-heteroarylcyclohexylamino) cyclopentanecarboxamides as chemokine receptor modulators | INCYTE CORP (US) | 2007-04-18 | — | — | CN | disclosed |