SCHEMBL2766099

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2766104	1.00	ADAMTS5 (0.53)	ADAMTS5MMP14ALDH1A1HPGDMEN1
	SCHEMBL2763946	0.89	ADAMTS5 (0.66)	ADAMTS5MMP14ALDH1A1MEN1KMT2A
	SCHEMBL2763947	0.89	ADAMTS5 (0.66)	ADAMTS5MMP14ALDH1A1MEN1KMT2A
	SCHEMBL6058671	0.89	ADAMTS5 (0.50)	ADAMTS5MMP14TP53MAPK1CYP2C19
	SCHEMBL2764219	0.89	ADAMTS5 (0.50)	ADAMTS5MMP14TP53MAPK1CYP2C19
	SCHEMBL2764220	0.89	ADAMTS5 (0.50)	ADAMTS5MMP14TP53MAPK1CYP2C19
	SCHEMBL5492251	0.86	ADAMTS5 (0.52)	ADAMTS5MMP14ALDH1A1MEN1KMT2A
	SCHEMBL2766293	0.86	ADAMTS5 (0.52)	ADAMTS5MMP14ALDH1A1MEN1KMT2A
	SCHEMBL2766291	0.86	ADAMTS5 (0.52)	ADAMTS5MMP14ALDH1A1MEN1KMT2A
	SCHEMBL2764718	0.83	ADAMTS5 (0.53)	ADAMTS5MMP14ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.