Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 4/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24983697 | 0.81 | CFTR (0.51) | CFTRLMNATSHRKDM4EMAPT | |
| SCHEMBL3912237 | 0.79 | LDHA (0.54) | CFTREGFRLMNALDHASLC6A3 | |
| SCHEMBL6636502 | 0.79 | CFTR (0.47) | CFTRGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL8059705 | 0.79 | CFTR (0.53) | CFTRGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL12121707 | 0.78 | GABRA1 (0.62) | CFTRGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL23768065 | 0.77 | CFTR (0.48) | CFTRLMNATSHRKDM4EMAPT | |
| SCHEMBL28622866 | 0.76 | ACMSD (0.49) | CFTRBACE1 | |
| SCHEMBL23754415 | 0.76 | CFTR (0.61) | CFTRLMNATSHRKDM4EMAPT | |
| SCHEMBL2242947 | 0.76 | CFTR (0.57) | CFTRTSHRALDH1A1KDM4EMAPT | |
| SCHEMBL6639916 | 0.76 | CFTR (0.45) | CFTRGABRA1GABRG2GABRB3GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1882323-A | Substituted benzofuran oximes | WYETH CORP (US) | 2006-12-20 | — | — | CN | disclosed |