Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 1/20 | 0.69 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.64 |
| ▸ | NPC1 | O15118 | 8/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | SCD | O00767 | 1/20 | 0.59 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.57 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657614 | 0.92 | RAB9A (0.67) | AGERNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4285954 | 0.85 | NPC1 (0.85) | AGERADORA2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5502572 | 0.83 | AGER (0.76) | AGERADORA2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5502348 | 0.83 | AGER (0.60) | AGERADORA2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4297875 | 0.83 | ADORA2A (0.67) | AGERADORA2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16603980 | 0.82 | AGER (1.00) | AGERADORA2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4287847 | 0.80 | AGER (0.76) | AGERADORA2ANPC1RAB9ASMN1; SMN2 | |
| Cycloheptane SCHEMBL5500214 | 0.80 | AGER (0.71) | AGERADORA2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8298569 | 0.78 | AGER (0.73) | AGERADORA2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4290771 | 0.78 | NPC1 (0.79) | AGERADORA2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1870996-A | N-thiazol-2-yl-benzamide derivatives | LUNDBECK & CO AS H (DK) | 2006-11-29 | — | — | CN | claimed |