Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 1/20 | 0.76 |
| ▸ | NPC1 | O15118 | 7/20 | 0.73 |
| ▸ | RAB9A | P51151 | 6/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.71 |
| ▸ | SCD | O00767 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.63 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cycloheptane SCHEMBL5500214 | 0.96 | AGER (0.71) | AGERNPC1RAB9ASMN1; SMN2ADORA2A | |
| SCHEMBL4285954 | 0.90 | NPC1 (0.85) | AGERNPC1RAB9ASMN1; SMN2ADORA2A | |
| SCHEMBL16603980 | 0.87 | AGER (1.00) | AGERNPC1RAB9ASMN1; SMN2ADORA2A | |
| SCHEMBL4290771 | 0.86 | NPC1 (0.79) | AGERNPC1RAB9ASMN1; SMN2ADORA2A | |
| SCHEMBL4287847 | 0.85 | AGER (0.76) | AGERNPC1RAB9ASMN1; SMN2ADORA2A | |
| SCHEMBL3223685 | 0.84 | RAB9A (1.00) | AGERNPC1RAB9ASMN1; SMN2ADORA2A | |
| SCHEMBL995829 | 0.84 | NPC1 (1.00) | AGERNPC1RAB9ASMN1; SMN2SCD | |
| SCHEMBL27664693 | 0.83 | AGER (0.69) | AGERNPC1RAB9ASMN1; SMN2ADORA2A | |
| SCHEMBL8298569 | 0.83 | AGER (0.73) | AGERNPC1RAB9ASMN1; SMN2ADORA2A | |
| Hydrochloric Acid SCHEMBL27594584 | 0.83 | NPC1 (0.97) | AGERNPC1RAB9ASMN1; SMN2SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682129-B1 | N-THIAZOL-2-YL-BENZAMIDE DERIVATIVES | LUNDBECK & CO AS H (DK) | 2007-02-21 | — | — | EP | claimed |
| CN-1870996-A | N-thiazol-2-yl-benzamide derivatives | LUNDBECK & CO AS H (DK) | 2006-11-29 | — | — | CN | disclosed |