Sugi Predict

Sugi Predict / Compounds / SCHEMBL276649

SCHEMBL276649

SCHEMBL276649

COC(=O)C(N)CCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ LTA4H P09960 3/20 0.53
▸ LNPEP Q9UIQ6 4/20 0.52
▸ ERAP2 Q6P179 2/20 0.52
▸ TSHR P16473 1/20 0.50
▸ METAP2 P50579 1/20 0.50
▸ METAP1 P53582 1/20 0.50
▸ CTSC P53634 1/20 0.49
▸ SMN1; SMN2 Q16637 2/20 0.49
▸ ANPEP P15144 2/20 0.49
▸ ERAP1 Q9NZ08 2/20 0.49
▸ MEN1 O00255 1/20 0.47
▸ HTT P42858 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5019109 1.00 LTA4H (0.53) LTA4HLNPEPERAP2TSHRMETAP2
SCHEMBL1841055 1.00 LTA4H (0.53) LTA4HLNPEPERAP2TSHRMETAP2
Hydrochloric Acid SCHEMBL4634588 0.98 LTA4H (0.52) LTA4HLNPEPERAP2TSHRMETAP2
Hydrochloric Acid SCHEMBL4634585 0.98 LTA4H (0.52) LTA4HLNPEPERAP2TSHRMETAP2
Hydrochloric Acid SCHEMBL17713350 0.98 LTA4H (0.52) LTA4HLNPEPERAP2TSHRMETAP2
Trifluoroacetic Acid SCHEMBL7023585 0.91 LTA4H (0.47) LTA4HLNPEPERAP2TSHRMETAP2
SCHEMBL1279303 0.90 GRIK1 (0.55) LTA4HKMT2A
SCHEMBL7274943 0.90 GRIK1 (0.55) LTA4HKMT2A
Hydrochloric Acid SCHEMBL5758683 0.89 GRIK1 (0.54) LTA4HKMT2A
SCHEMBL2523775 0.89 LTA4H (0.50) LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106188224-A A kind of multiple target-point anti-cancer medicine and preparation method and application 广东工业大学 2016-12-07 — — CN claimed
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 — — US disclosed
US-12371461-B2 Nemo coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2025-07-29 — — US disclosed
EP-3303367-B1 STABILIZED MINIMAL COILED-COIL MIMETICS UNIV NEW YORK (US) 2025-06-18 — — EP disclosed
US-20240190930-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME UNIV NEW YORK (US) 2024-06-13 — — US disclosed
US-20240124539-A1 CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME NEW YORK UNIVERSITY 2024-04-18 — — US disclosed
US-11891422-B2 NEMO coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2024-02-06 — — US disclosed
US-20240034753-A1 THERAPEUTIC PEPTIDES COHBAR, INC. 2024-02-01 — — US disclosed
US-11753445-B2 Therapeutic peptides COHBAR, INC. (US) 2023-09-12 — — US disclosed
US-20230234917-A1 ASPARAGINE DERIVATIVES AND METHODS OF USING SAME SENDA BIOSCIENCES INC (US) 2023-07-27 — — US disclosed
US-5658935-A USEFUL AS INHIBITORS OF THROMBOCYTE AGGREGATION, THE METASTASIS OF CARCINOMA CELLS AND THE BINDING OF OSTEOCLASTS ON BONE SURFACES HOECHST AKTIENGESELLSCHAFT (DE) 1997-08-19 — — US disclosed
US-5552318-A ENANTIOSELECTIVE SYNTHESIS OF D-AMINO ACIDS INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1996-09-03 — — US disclosed
US-5552317-A POLYMERIZATION OF MONOMERS IN THE PRESENCE OF ENZYME AND HYDROLYSIS INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1996-09-03 — — US disclosed
EP-0701561-A1 DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 LABORATORIOS MENARINI S.A. (ES) 1996-03-20 — — EP disclosed
WO-1994028004-A1 DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 LABORATORIOS MENARINI S.A. (ES) 1994-12-08 — — WO disclosed
US-4808713-A Anthypertensive pyridazo [1,2-a][1,2]diazepines HOFFMAN-LA ROCHE INC. (US) 1989-02-28 — — US disclosed
US-4772701-A Pyridazo[1,2]pyridazines and pyrazolo[1,2]pyridazines as antihypertensives HOFFMANN-LA ROCHE INC. (US) 1988-09-20 — — US disclosed
US-4658024-A Pyrazolo [1,2-a][1,2]-diazepines useful as antihypertensives HOFFMANN-LA ROCHE INC. (US) 1987-04-14 — — US disclosed
US-4512924-A HYPOTENSIVE AGENTS HOFFMANN-LA ROCHE INC. (US) 1985-04-23 — — US disclosed
EP-0094095-A2 Bicyclic carboxylic acids and their alkyl and aralkyl esters F. HOFFMANN-LA ROCHE AG (CH) 1983-11-16 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371461-B2 Nemo coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH LTA4H 2470/4885LNPEP 3227/4885ERAP2 2785/4885
US-20230234917-A1 ASPARAGINE DERIVATIVES AND METHODS OF USING SAME ASNS, SI, NARS1 LTA4H 1886/4885LNPEP 37/4885ERAP2 455/4885
US-20240124539-A1 CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME SOS2, SOS1, F2 LTA4H 2991/4885LNPEP 4588/4885ERAP2 4295/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 LTA4H 2089/4885LNPEP 1755/4885ERAP2 3459/4885
US-11891422-B2 NEMO coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH LTA4H 2470/4885LNPEP 3227/4885ERAP2 2785/4885
US-20240190930-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME COIL, CALCOCO2, NCAPH LTA4H 2561/4885LNPEP 3412/4885ERAP2 3198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.