Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | GRM5 | P41594 | 5/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | CCR8 | P51685 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28967118 | 0.86 | MEN1 (0.38) | RAB9AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11712255 | 0.80 | RAB9A (0.55) | RAB9AMEN1KMT2AGRM5CCR1 | |
| SCHEMBL1861757 | 0.80 | RAB9A (0.55) | RAB9AMEN1KMT2AGRM5CCR1 | |
| SCHEMBL19151683 | 0.75 | RAB9A (0.53) | RAB9AMEN1KMT2AGRM5CCR1 | |
| SCHEMBL15765836 | 0.74 | RAB9A (0.52) | RAB9AMEN1KMT2AGRM5CCR1 | |
| SCHEMBL229747 | 0.72 | RAB9A (0.59) | RAB9AMEN1KMT2AGRM5CCR1 | |
| SCHEMBL306134 | 0.70 | — | — | |
| SCHEMBL30558522 | 0.70 | — | — | |
| SCHEMBL19915750 | 0.69 | — | — | |
| SCHEMBL2007460 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1964946-A | 2-propen-1-ones as HSP 70 inducers | TORRENT PHARMACEUTICALS LTD (IN) | 2007-05-16 | — | — | CN | disclosed |