Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | KDM5C | P41229 | 4/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.43 |
| ▸ | KDM6B | O15054 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18652185 | 0.83 | PHF8 (0.46) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL4028377 | 0.79 | PHF8 (0.43) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL8022557 | 0.77 | TSHR (0.33) | — | |
| SCHEMBL9500008 | 0.76 | RECQL (0.42) | KDM4EALDH1A1 | |
| Oxalic Acid SCHEMBL9795316 | 0.76 | FNTA (0.41) | ALDH1A1 | |
| SCHEMBL5940256 | 0.76 | MEN1 (0.46) | MEN1CYP1A2KMT2A | |
| SCHEMBL2040611 | 0.75 | — | — | |
| SCHEMBL11222029 | 0.75 | FAAH (0.60) | MEN1KMT2A | |
| SCHEMBL2873904 | 0.75 | LMNA (0.32) | LMNAKMT2A | |
| Oxalic Acid SCHEMBL9795337 | 0.74 | FNTA (0.43) | KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1882548-A | pH-sensitive prodrugs of 2, 6-diisopropylphenol | AUSPEX PHARMACEUTICALS INC (US) | 2006-12-20 | — | — | CN | disclosed |