SCHEMBL8022557

SCHEMBL8022557

C=CNC(=O)CCC(=O)NCC(C)(C)N

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.33
FAAH O00519 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27665147 0.77 PHF8 (0.46)
SCHEMBL6656224 0.71 ALDH1A1 (0.50) TSHR
SCHEMBL9500008 0.70 RECQL (0.42) TSHRSMN1; SMN2FAAH
SCHEMBL223004 0.70 ALDH1A1 (0.33) TSHRSMN1; SMN2MAPT
SCHEMBL31364147 0.70 KDM4E (0.52) TSHRSMN1; SMN2MAPT
SCHEMBL5940256 0.70 MEN1 (0.46) SMN1; SMN2
SCHEMBL8017389 0.69 CNR1 (0.43) MAPTFAAH
SCHEMBL11222029 0.69 FAAH (0.60) FAAH
SCHEMBL2873904 0.69 LMNA (0.32)
Hydrochloric Acid SCHEMBL23001647 0.69 KDM4E (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0762197-B1 Photographic recording material AGFA GEVAERT AG (DE) 2000-01-12 EP disclosed
EP-0643326-B1 New type of polymer latex and its use as plasticizer in a photographic material AGFA GEVAERT NV (BE) 1999-12-01 EP disclosed
US-5888719-A CONTINING A POLYMER; DARK DECAY STABILITY AGFA-GEVAERT AG (DE) 1999-03-30 US disclosed
US-5674668-A Photographic recording material AGFA-GEVAERT (DE) 1997-10-07 US disclosed
EP-0762197-A1 Photographic recording material Agfa-Gevaert AG (DE) 1997-03-12 EP disclosed
US-5518877-A POLYPEPTIDE-ADDITION POLYMER AGFA-GEVAERT AG (DE) 1996-05-21 US disclosed
US-5478710-A Obtained by radical emulsion polymerization; glass transition temperature AGFA-GEVAERT, N.V. (BE) 1995-12-26 US disclosed
EP-0666498-A2 Silver halide photographic material Agfa-Gevaert AG (DE) 1995-08-09 EP disclosed
EP-0643326-A1 New type of polymer latex and its use as plasticizer in a photographic material AGFA-GEVAERT N.V. (BE) 1995-03-15 EP disclosed
US-5015566-A Silver halide emulsion coated on a support, hydrophobic colloids EASTMAN KODAK COMPANY (US) 1991-05-14 US disclosed
EP-0358187-A2 Tabular grain photographic elements exhibiting reduced pressure sensitivity (II) EASTMAN KODAK COMPANY (US) 1990-03-14 EP disclosed
US-4082551-A GOOD ADHESION AND BLOCKING POSITIVE CHARGED PARTICLES EASTMAN KODAK COMPANY (US) 1978-04-04 US disclosed