Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | SELP | P16109 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9795316 | 0.98 | FNTA (0.41) | FNTAFNTBGAAPTPN1GPR84 | |
| SCHEMBL9500008 | 0.93 | RECQL (0.42) | FNTAFNTBGAAPTPN1GPR84 | |
| SCHEMBL11222029 | 0.81 | FAAH (0.60) | FAAHNAAADNM1MEN1KMT2A | |
| Oxalic Acid SCHEMBL9795258 | 0.78 | ALDH1A1 (0.43) | PTPN1FAAHRECQL | |
| Oxalic Acid SCHEMBL9795310 | 0.77 | KDM4E (0.36) | FNTAFNTBGAAPTPN1FAAH | |
| SCHEMBL9498341 | 0.76 | RECQL (0.40) | FNTAFNTBGAAPTPN1GPR84 | |
| Oxalic Acid SCHEMBL9795355 | 0.73 | FFAR1 (0.36) | FFAR1TDP1 | |
| Oxalic Acid SCHEMBL9795198 | 0.72 | FNTA (0.44) | FNTAFNTBGAAPTPN1GPR84 | |
| SCHEMBL11520316 | 0.71 | RECQL (0.41) | GAAPTPN1FAAHRECQLTDP1 | |
| SCHEMBL17227253 | 0.70 | NAAA (0.46) | PTPN1FAAHRECQLTDP1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |