Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.33 |
| ▸ | MMP3 | P08254 | 3/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27665623 | 0.93 | BLM (0.34) | MMP2MMP3BLMALDH1A1CYP3A4 | |
| SCHEMBL27643971 | 0.88 | BLM (0.33) | BLMALDH1A1CYP3A4CYP1A2KDM4E | |
| SCHEMBL27643953 | 0.88 | LMNA (0.36) | BLMALDH1A1CYP3A4CA2HDAC3 | |
| SCHEMBL27665564 | 0.88 | CYSLTR2 (0.34) | MMP2MMP3BLMPOLB | |
| SCHEMBL27644741 | 0.87 | TAAR1 (0.36) | ALDH1A1CYP3A4CA2MEN1HPGD | |
| SCHEMBL27665338 | 0.87 | KDM4E (0.36) | BLMALDH1A1CYP3A4L3MBTL1CYP1A2 | |
| SCHEMBL27665657 | 0.86 | NR3C1 (0.37) | BLMALDH1A1CYP3A4L3MBTL1CYP1A2 | |
| SCHEMBL27665807 | 0.85 | KDM4E (0.36) | CA2TSHRKDM4EGAAADRA1A | |
| SCHEMBL27665770 | 0.85 | POLB (0.36) | BLMGLATSHRHTTL3MBTL1 | |
| SCHEMBL27643955 | 0.84 | L3MBTL1 (0.36) | ALDH1A1GLAL3MBTL1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |