Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27665623 | 0.87 | BLM (0.34) | NR3C1BLMCYP1A2ALDH1A1POLB | |
| SCHEMBL27644798 | 0.87 | BLM (0.36) | BLMCYP1A2ALDH1A1POLBGAA | |
| SCHEMBL27665381 | 0.86 | MMP2 (0.33) | BLMCYP1A2ALDH1A1POLBGAA | |
| SCHEMBL27644201 | 0.85 | KDM4E (0.39) | NR3C1BLMCYP1A2ALDH1A1POLB | |
| SCHEMBL27644402 | 0.85 | ALDH1A1 (0.40) | BLMCYP1A2ALDH1A1POLBGAA | |
| SCHEMBL27644009 | 0.85 | NR3C1 (0.41) | NR3C1BLMCYP1A2ALDH1A1POLB | |
| SCHEMBL28761473 | 0.84 | PPARG (0.39) | NR3C1BLMALDH1A1GAAHPGD | |
| SCHEMBL28761468 | 0.84 | BLM (0.37) | NR3C1BLMCYP1A2ALDH1A1POLB | |
| SCHEMBL27643944 | 0.82 | BLM (0.34) | BLMCYP1A2ALDH1A1POLBGAA | |
| SCHEMBL27644080 | 0.82 | TSHR (0.39) | BLMCYP1A2ALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |