SCHEMBL2766552

SCHEMBL2766552

Cl[Mn](Cl)C(n1nc(-c2ccccc2)cc1-c1ccccc1)(n1nc(-c2ccccc2)cc1-c1ccccc1)n1nc(-c2ccccc2)cc1-c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 6/20 0.45
MAPT P10636 3/20 0.40
POLB P06746 1/20 0.40
ALDH1A1 P00352 4/20 0.38
TP53 P04637 2/20 0.38
KDM4E B2RXH2 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
MAPK1 P28482 1/20 0.37
MCL1 Q07820 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
EGFR P00533 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2766528 0.82 KDM4E (0.43) MAPTALDH1A1KDM4ESMN1; SMN2HPGD
SCHEMBL2766012 0.75 P2RY6 (0.47) P2RY6MAPTPOLBALDH1A1TP53
SCHEMBL27890734 0.73 TP53 (0.47) P2RY6MAPTALDH1A1TP53KDM4E
SCHEMBL2458758 0.69 MAPT (0.61) P2RY6MAPTPOLBALDH1A1TP53
SCHEMBL6472800 0.69 ALDH1A1 (0.36) P2RY6MAPTPOLBALDH1A1TP53
SCHEMBL2766813 0.69 KMT2A (0.48) MAPTALDH1A1TP53KDM4ESMN1; SMN2
SCHEMBL2766550 0.68 MAPT (0.55) P2RY6MAPTPOLBALDH1A1TP53
SCHEMBL26459294 0.67 MAPT (0.46) MAPTPOLBALDH1A1KDM4ESMN1; SMN2
SCHEMBL822565 0.67 ALDH1A1 (0.53) MAPTPOLBALDH1A1
SCHEMBL27890801 0.67 MAPT (0.55) MAPTALDH1A1KDM4ESMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1266911-B1 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL CO (JP) 2010-04-14 EP disclosed
US-6881802-B2 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-04-19 US disclosed
US-20030032743-A1 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-02-13 US disclosed
EP-1266911-A1 Catalyst for addition polymerization and process for producing an addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030032743-A1 Catalyst for addition polymerization and process for producing an addition polymer BRAP, MCM4, BOLA2; BOLA2B P2RY6 2014/4885MAPT 749/4885POLB 790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.